Search for a UniProtKB Accession (e.g. P12345) to identify which method provide HOGs at which taxonomic range, and then to compare their members.
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HOG in OMA
HOG in OrthoDB
Orthologs in OMA
Orthologs in OrthoDB
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Under the SwissOrthology umbrella the SIB provides a variety of resources centered around orthology. Orthologs are genes that have started diverging through a speciation event. As they have been by definition the same gene until speciation, orthologs play an important role in many bioinformatics applications such as gene function prediction, species tree reconstruction or comparative analyses.
SwissOrthology is a collaboration between the two research labs run by Christophe Dessimoz at University Lausanne and Evgeny Zdobnov at University of Geneva. The two labs develop and maintain two of the world leading resources for orthology: Orthology MAtrix and OrthoDB.
Find out more about the collaboration.
In the interactive guide we try to help you to find the right orthology resource for your application.